yes, it happens to me twice.
The strange thing is if I eject the disc and going back to PS main screen/theme system, it will freeze the system again after I put back the game in. Now, if I eject the disc and unplug the system without turning it off, the system will go restoring file system, put back the disc in, it plays fine after that.
And the games that causing freeze are Infamous 1 and Uncharted 1. Both are GH versions.
Well it started happening to me after i have bought a Red Dead Redemption,while other games like gt5 are running perfectly,rdr freezes every 5-10 mins,but that may be caused by a dirty lens because gt5 is fully installed on the hdd and rdr has only 600 mb in the game files and the rest is read from the disc.Only thing i know that my hdd is not damaged because digitally downloaded games and fully installed ones are working perfectly.Rdr disc is also okay,it has a few scratches but mostly from the console itself because im very carefull with my discs.