Drakes tranquilizer gun. I feel like it must have a purpose, but...it doesnt O_o
Radec's up square, useless compared to his arc rifle and especially his shotgun.
Sir Dan's dragon potion. Doesn't do anywhere near enough damage to be effective.
Ratchet's...buzz blades i guess. But even they have their uses. Maybe i'm just forgetting something.
Big Daddy's Fire. Never found a place to use it.
The tranq gun if good for getting back on the ground because Drake shouldn't be in the air for extended periods of time.
Evil Cole - Up Square, might as well do up Triangle if you're going after someone up above, at least the Triangle one moves upward and can bounce opponents for another round.
Sweet Tooth - Machete Toss, plain and simple
Radec - Another useless up square with that quick shotgun blast, I never think to use it because the hitbox is never where I need it
Ratchet - Neutral O sniper shot, the only good thing I use that for is to stop mid-air if I feel landing would be a bad idea at the moment. Rarely do I react fast enough to be able to blast someone with the gun itself