Getting back to serious:
Playstation vs Xbox
I'd love to see the characters duke it out with each other, i feel Sony has always had more of a rivalry with Microsoft than Nintendo, this would be a pretty epic way of letting the players fight in that rivalry, of course it will NEVER HAPPEN, but it would be pretty sweet, i'd love to see Kratos vs Master Chief or Toro vs the Word paper clip
Looking over this post, I've really got to disagree. Watch this:
Those guys at Nintendo were responsible for the betrayal that would lead to the creation of the console which would unseat them twice in a row. We're their greatest enemy, and vice-versa (Sega was just a speed-bump for them). The fact that the PSP has been the most successful non-Nintendo portable in history should say a lot after they cornered that market so thoroughly.
Now that the PS3 has outsold the 360 despite their year-headstart, we're in second-place for this generation, proving that we always come back to haunt Nintendo.